Texas Longhorns running back Quintrevion Wisner (5) runs down the sideline during the first half against the Texas A&M Aggies at Darrell K Royal-Texas Memorial Stadium on Nov. 28, 2025. (Scott Wachter/Imagn Images)
Week 4 of the College Football schedule is delivering some excellent games and matchups and there are plenty of ways for you to bet on the action all day long from sportsbooks like FanDuel, Caesars Sportsbook, Fanatics Sportsbook, and bet365.
The main event for today is the matchup between Texas and Tennessee. We have the top ranked Longhorns going on the road to face Tennessee. The Volunteers haven’t fared well against top ranked teams in their history, but if they can get their running game going, an upset might be in order.
Iowa vs. Michigan features two teams right next to each other in the standings. Iowa is 17th, and Michigan is 18th. It seems like the Wolverines have been flirting with a loss all season, and Iowa is poised to try to deliver it. Big 10 matchups are always fun to watch, and this could come down to whichever team can make a big pass at a critical time.
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One other great matchup worth watching tonight is Ole Miss heading into Gainesville, Florida to face the Gators after a very emotional victory last week. How quickly can Ole Miss refocus and prepare for another big test – this time on the road? Will Florida be able to hang with one of the toughest teams in the nation? The answer to these questions comes at 3:30 ET.
FanDuel
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Texas vs Tennessee
Odds subject to change
| Spread | Total | Moneyline | |
| Texas | -4 (-110) | O 55.5 (-105) | -192 |
| Tennessee | +4 (+110) | U 55.5 (-115) | +160 |
Fanatics
How to Sign Up and Claim the Fanatics Sportsbook Welcome Bonus
- Visit Fanatics Sportsbook by clicking the applicable “Claim Bonus” button on this page.
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Iowa vs Michigan
Odds subject to change
| Spread | Total | Moneyline | |
| Iowa | +5.5 (-110) | O 38.5 (-112) | +180 |
| Michigan | -5.5 (-110) | U 38.5 (-108) | -218 |
Caesars Sportsbook
How to Claim the Caesars Sportsbook Promo Code FOXNEWSDYW
- Visit Caesars Sportsbook via this link to automatically apply promo code FOXNEWSDYW
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Ole Miss vs. Florida
Odds subject to change
| Spread | Total | Moneyline | |
| Ole Miss | +3.5 (-120) | O 59.5 (-102) | +130 |
| Florida | -3.5 (+100) | U 59.5 (-118) | -155 |
Bet365
How to claim bet365 Promo
- Click this “Claim Bonus” button to go directly to bet365.
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Oregon vs USC
Odds subject to change
| Spread | Total | Moneyline | |
| Oregon | -3 (-112) | O 62.5 (-108) | -162 |
| USC | +3 (-108) | U 62.5 (-112) | +136 |
College Football Schedule
Saturday, September 26
Noon Window (12:00 PM ET)
- Texas at Tennessee — 12:00 PM ET (ABC)
- Illinois at Ohio State — 12:00 PM ET (FOX)
- Wake Forest at Louisville — 12:00 PM ET (ESPN)
- Colorado at Baylor — 12:00 PM ET (ESPN2)
- Virginia Tech at Boston College — 12:00 PM ET (ACCN)
- Colorado State at UTSA — 12:00 PM ET (ESPNU)
- San Diego State at Toledo — 12:00 PM ET (CBSSN)
- Sam Houston at Texas Tech — 12:00 PM ET (TNT / Max)
- Bucknell at Pittsburgh — 12:00 PM ET (ACCNX)
- UNLV at Akron — 12:00 PM ET (ESPN+)
- Ball State at Kent State — 12:00 PM ET (ESPN+)
- South Alabama at Kentucky — 12:45 PM ET (SECN)
Early Afternoon Window (1:00 PM – 2:00 PM ET)
- Lindenwood at Eastern Michigan — 1:00 PM ET (ESPN+)
- UCLA at Maryland — 1:30 PM ET (BTN)
- Notre Dame at Purdue — 2:00 PM ET (Peacock)
- Northern Illinois at Georgia State — 2:00 PM ET (ESPN+)
Mid-Afternoon Window (3:00 PM – 4:30 PM ET)
- Central Arkansas at Florida State — 3:00 PM ET (ACCN)
- Hawaii at Wyoming — 3:00 PM ET (The CW)
- Ole Miss at Florida — 3:30 PM ET (ABC)
- Oklahoma at Georgia — 3:30 PM ET (ESPN)
- Boise State at Western Michigan — 3:30 PM ET (ESPN2)
- Iowa at Michigan — 3:30 PM ET (CBS / Paramount+)
- Utah at Iowa State — 3:30 PM ET (FOX)
- TCU at UCF — 3:30 PM ET (FS1)
- New Mexico at New Mexico State — 3:30 PM ET (CBSSN)
- William & Mary at Duke — 3:30 PM ET (ACCNX)
- Gardner-Webb at Marshall — 3:30 PM ET (ESPN+)
- UConn at Miami (OH) — 3:30 PM ET (ESPN+)
- Robert Morris at Buffalo — 3:30 PM ET (ESPN+)
- Stonehill at Ohio — 3:30 PM ET (ESPN+)
- NC Central at East Carolina — 4:00 PM ET (ESPN+)
- Houston at Georgia Southern — 4:00 PM ET (ESPNU)
- Vanderbilt at Auburn — 4:15 PM ET (SECN)
Late Afternoon / Evening Window (5:00 PM – 7:00 PM ET)
- Wisconsin at Penn State — 5:00 PM ET (Peacock)
- Nebraska at Michigan State — 5:00 PM ET (BTN)
- South Florida at Bowling Green — 5:00 PM ET (ESPN+)
- Delaware at Virginia — 6:00 PM ET (ACCN)
- Incarnate Word at Texas State — 6:00 PM ET (USA)
- James Madison at Old Dominion — 6:00 PM ET (ESPN+)
- LIU at FIU — 6:00 PM ET (ESPN+)
- Central Michigan at Miami (FL) — 6:30 PM ET (The CW)
- Louisiana at Charlotte — 6:30 PM ET (ESPN+)
Prime Time Window (7:00 PM – 8:00 PM ET)
- South Carolina at Alabama — 7:00 PM ET (ESPN)
- Kansas State at Cincinnati — 7:00 PM ET (ESPN2)
- Oklahoma State at West Virginia — 7:00 PM ET (FS1)
- Southern Miss at Tulane — 7:00 PM ET (ESPN+)
- Kennesaw State at Arkansas State — 7:00 PM ET (ESPN+)
- Mercyhurst at Western Kentucky — 7:00 PM ET (ESPN+)
- Middle Tennessee at Jacksonville State — 7:00 PM ET (ESPN+)
- Texas A&M at LSU — 7:30 PM ET (ABC)
- Oregon at USC — 7:30 PM ET (NBC / Peacock)
- Arizona at Washington State — 7:30 PM ET (CBS / Paramount+)
- Troy at Utah State — 7:30 PM ET (CBSSN)
- Appalachian State at NC State — 7:30 PM ET (ESPNU)
- Houston Christian at North Texas — 7:30 PM ET (ESPN+)
- Missouri at Mississippi State — 7:45 PM ET (SECN)
- Tulsa at Arkansas — 8:00 PM ET (SECN+)
- Florida Atlantic at ULM — 8:00 PM ET (ESPN+)
Late Night Window (9:00 PM ET and later)
- Missouri State at SMU — 9:00 PM ET (ACCN)
- Oregon State at UTEP — 9:00 PM ET (MW+)
- UMass at Sacramento State — 9:00 PM ET (ESPN+)
- Rice at Fresno State — 10:00 PM ET (The CW)
- Georgia Tech at Stanford — 10:30 PM ET (ESPN)
- Air Force at Nevada — 10:30 PM ET (FS1)
- Minnesota at Washington — 11:00 PM ET (FOX)