LeBron James, Joel Embiid, Jaylen Brown and Tyrese Maxey look on during a preseason game against the Boston Celtics at Xfinity Mobile Arena in Philadelphia on Oct. 16, 2026. (Mitchell Leff/Getty Images)
The NBA is back after taking Election Day off, and it’s making up for lost time with 14 games on Wednesday’s schedule. The headliner tips at 7 p.m. ET on ESPN, where LeBron James, Tyrese Maxey and the 76ers visit Cade Cunningham and the Pistons in a rematch of two of the East’s best teams. Fanatics Sportsbook is offering new users promo code FOXNEWS350 to bet $20 and get $350 in FanCash on any game tonight.
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76ers vs Pistons | Wednesday, Nov. 4, 2026 at 7:00 p.m. ET | Little Caesars Arena, Detroit, MI | ESPN
These two already met once this season, when both came in at 2-0 in Philadelphia on Oct. 25, resulting in a 106-93 Pistons victory. That game was billed as an early statement between two contenders, and the rematch carries the same weight. Detroit finished last season atop the Eastern Conference, while Philadelphia added LeBron James and Jaylen Brown to a backcourt led by Tyrese Maxey and entered the year as one of the title favorites.
Cunningham is the engine for Detroit and has grown into a legitimate MVP candidate. He controls the pace, gets to his spots in the fourth quarter and carries a huge share of the scoring and playmaking. The big question for the Pistons as it has been the last year or so is support. Jalen Duren has been dealing with an injury, and without him, Detroit loses its best rebounder and interior finisher. Check his status before you bet.
There is no question that in 2026, Philadelphia brings more star power. Maxey is one of the league’s most explosive scorers, and LeBron gives the Sixers a second creator who can run the offense when Maxey sits. If Philly gets its transition game going in Detroit, it can win this one on the road.
The Pick: Cade Cunningham Points (Over)
If Duren is limited, Detroit’s offense runs through Cunningham even more than usual. He’s the player the Pistons trust in close games, and a nationally televised rematch with a contender is exactly the kind of night where he takes over. His points line is the cleanest way to bet on this game.
More Wednesday Headliners
Mavericks at Spurs closes the ESPN doubleheader at 9:30 p.m. ET, and Cavaliers at Thunder at 8 p.m. ET is one of the best matchups of the night.
Wednesday NBA Schedule
- Hawks at Wizards, 7:00 p.m. ET
- 76ers at Pistons, 7:00 p.m. ET (ESPN)
- Hornets at Nets, 7:30 p.m. ET
- Bulls at Knicks, 7:30 p.m. ET
- Bucks at Celtics, 7:30 p.m. ET
- Cavaliers at Thunder, 8:00 p.m. ET
- Pacers at Grizzlies, 8:00 p.m. ET
- Jazz at Pelicans, 8:00 p.m. ET
- Timberwolves at Rockets, 8:30 p.m. ET
- Trail Blazers at Suns, 9:00 p.m. ET
- Raptors at Nuggets, 9:00 p.m. ET
- Mavericks at Spurs, 9:30 p.m. ET (ESPN)
- Lakers at Kings, 10:00 p.m. ET
- Heat at Clippers, 10:30 p.m. ET
Fourteen games and a heavyweight rematch in Detroit. New users can bet $20 on 76ers-Pistons or any NBA game tonight and get $350 in FanCash with Fanatics Sportsbook promo code FOXNEWS350.