Wilder has been trying to organise a blockbuster unification fight against Anthony Joshua and a rematch with Tyson Fury over recent months.
But first he has opted to put his WBC heavyweight belt on the line against Dominic Breazeale on May 18.
After that, the American will get back to the negotiation table to try and convince Joshua or Fury to step into the ring with him.
However, if he was to knockout either of those Brits, it could come with horrific consequences.
“You in trouble now,” he told the Daily Mail ahead of a sparring session.
“You in big trouble now. You going to be eating hospital food. I heard that’s terrible. I’m almost starting to feel sorry for you.
“The only way you can hurt a man severely and get paid for it.
“I get paid for my work and I love it. Best job in the world. Some people say it it’s a sin to hit that hard.
“If this man goes down and he does not wake up, it will be you guys’ fault. You asked for it.
“I am not going to feel no remorse, no sympathy, no sorrow. Tick, tock. Another fight, another day, another time, another place.”
Wilder was pushed further on if he was really willing to kill somebody in the ring.
“Not one bit of remorse,” Wilder added.
“Because this is boxing. This is what we do. This is what we sign up for.
“People on the outside will never understand this sport. They will never understand what we have to go through, break our body down.
“We are fighting for our lives in the ring anyway. Anything can happen. Your head is not meant to be hit in the first place. One little tap can end it all.
“You talk about me killing the guy? If it happens, it happens. When you are dealing with a situation like this and it’s personal, I don’t mean well for him, nor do he mean well for me.”