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Home»Health»Scientists crack code on how dietary fiber shields your body from harmful sugar damage
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Scientists crack code on how dietary fiber shields your body from harmful sugar damage

nytimespostBy nytimespostOctober 12, 2025No Comments
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A new UC Irvine study may have finally uncovered how dietary fiber protects the body from sugar’s damage, and how protecting yourself starts in the gut.

Researchers at the UCI School of Medicine found that inulin, a naturally occurring fiber found in vegetables like onions, garlic and artichokes, can reshape the bacteria living in your gut to stop fructose before it hits your liver.

“We found that consuming a type of dietary fiber called inulin… changes the bacteria in the gut to promote the consumption of harmful dietary fructose,” said lead researcher Cholsoon Jang, PhD, of UCI’s Nutrient Metabolism & Disease Lab. 

The findings, published in Nature Metabolism, reveal a new level of protection offered by fiber, not just in digestion, but in how the body handles sugar at the molecular level.

ACTRESS KRISTEN BELL’S EASY DIET TRICK TO HELP STABILIZE BLOOD SUGAR

Woman holding her belly suffering from abdominal pain

Scientists say fiber could help prevent or reverse early signs of fatty liver disease. (iStock)

Jang and his team discovered that when people eat fructose (a common sugar in fruit and sweetened foods) gut bacteria in the small intestine can metabolize it before it reaches the liver. But without enough fiber, too much fructose “spills over,” overwhelming the liver and triggering fat buildup.

RISK OF COLON CANCER SLASHED BY EATING SPECIFIC TYPES OF VEGETABLES, STUDY FINDS

Woman washing fresh fruit in the kitchen

Fructose is a sugar found in fruit that can ‘spill’ into the liver, leading to liver disease. (iStock)

By feeding gut bacteria with inulin, researchers found that the microbes essentially burn through fructose early, preventing that cascade of damage. 

Even more striking, once these bacteria were “primed” by inulin, they were able to reverse signs of fatty liver disease, reducing fat accumulation and boosting the liver’s natural antioxidants.

EXPERTS REVEAL 5-STEP APPROACH TO A HEALTHIER GUT AND STRONGER IMMUNITY

Jang says the research proves not all calories are created equal.

He says their work gives “insight into how fiber protects our health from harmful nutrients like fructose.”

Photo representing gut bacteria, close-up 3D modeling

The Nature Metabolism study identified how specific gut bacteria metabolize sugar before it reaches the liver. (iStock)

The study focused on non-obese participants: people who might otherwise slip under the radar yet still face hidden risks from high-sugar diets. 

Jang noted that metabolic damage isn’t limited to those who are overweight. Even people who appear healthy can experience liver stress and insulin resistance if their gut microbes aren’t equipped to handle excess fructose.

“By identifying specific gut bacteria and metabolic pathways involved, our findings can guide personalized nutrition strategies,” Jang said.

Garlic, onion and Spanish onion on a wooden plate, seasoning vegetables on a wooden kitchen table top

Vegetables like garlic, artichokes and onions can be a good source of inulin, the helpful fiber studied by the research team. (iStock)

He added that future research will explore whether other common fibers beyond inulin can trigger similar protective effects.

MORE IN HEALTH NEWS

The implications stretch far beyond the lab. If certain fibers can train gut microbes to neutralize sugar before it harms the liver, it could open the door to new treatments for fatty liver disease, diabetes, obesity and even cancer.

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For now, researchers explain that the findings indicate that fiber not only aids digestion but can be a defender of metabolic health.

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As Jang put it: “For example, by checking how well someone’s gut bacteria clears fructose before the body absorbs it, we can choose the right prebiotic or probiotic supplement for that person to improve results and reduce side effects.”

Khloe Quill is a lifestyle production assistant with Fox News Digital. She and the lifestyle team cover a range of story topics including food and drink, travel, and health. 

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